Two cases of macrolide resistance in Mycoplasma pneumoniae acquired during the treatment period.

remains unclear, but given the patient’s history, a direct crossborder origin could be excluded. Since the blaIMP-19-carrying plasmid could not be mobilized, its contribution in terms of carriage of additional resistance genes could not be assessed and further investigations will be necessary to understand the potential advantage conferred by acquisition of this plasmid by the VIM-producing strain. Nevertheless, the detection of blaIMP-19 in a P. aeruginosa strain of the CC235 epidemic lineage is of concern, since this could promote blaIMP-19 dissemination in the clinical setting.